Thomas, West, and Pierce later explained that the experiment was designed to find out if LSD would induce musth in an elephant. The researchers figured that, if they were going to give an elephant LSD, they better not give him too little since they knew that elephants are highly resistant to many drugs. In fact, it remains the largest dose of LSD (that we know of) ever given to a living creature. It's about 3000 times the level of a typical human dose. With Thomas were two scientific colleagues from the University of Oklahoma School of Medicine, Louis Jolyon West and Chester M. Warren Thomas, Director of the City Zoo, fired a cartridge-syringe containing 297 milligrams of LSD into Tusko the Elephant's rump. What happens if you give an elephant LSD? On Friday August 3, 1962, a group of Oklahoma City researchers decided to find out.
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